4-Amino-2-Methoxy-Benzoic Acid Methyl Ester
Methyl 4-amino-2-methoxybenzoate
CAS: 27492-84-8
Molecular Formula: C9H11NO3
4-Amino-2-Methoxy-Benzoic Acid Methyl Ester - Names and Identifiers
4-Amino-2-Methoxy-Benzoic Acid Methyl Ester - Physico-chemical Properties
| Molecular Formula | C9H11NO3 |
| Molar Mass | 181.19 |
| Density | 1.179±0.06 g/cm3(Predicted) |
| Melting Point | 155-159 °C (lit.) |
| Boling Point | 339.2±22.0 °C(Predicted) |
| Flash Point | 181.8°C |
| Solubility | Chloroform (Slightly), Methanol (Slightly, Heated) |
| Vapor Presure | 9.36E-05mmHg at 25°C |
| Appearance | White solid |
| Color | White |
| pKa | 2.04±0.10(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.55 |
| MDL | MFCD00017202 |
4-Amino-2-Methoxy-Benzoic Acid Methyl Ester - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| WGK Germany | 2 |
| Hazard Class | IRRITANT |
4-Amino-2-Methoxy-Benzoic Acid Methyl Ester - Reference Information
| introduction | methyl 2-methoxy-4-aminobenzoate has a melting point of 155 to 159 degrees, a boiling point of 339.2±22.0 degrees (at one atmosphere), a density of 1.2, and a white or off-white solid at normal temperature and pressure. Methyl 2-methoxy-4-aminobenzoate is a commercial organic synthon. It has general solubility in chloroform and dichloromethane. It will be better when heated, but its solubility in water is poor. It can be used as an intermediate in organic synthesis. |
| Use | Methyl 2-methoxy-4-aminobenzoate is a common organic synthesis intermediate. The ester group in the structure can be easily converted into a variety of active functional groups, including hydroxyl and aldehyde groups. In addition, the ester group can also obtain the corresponding amide compound through the urethane exchange reaction. The amino group can be diazotized to obtain the corresponding diazonium salt and then converted into various active functional groups. In addition, because amino and methoxy groups are both strong electron donating groups, the electron cloud density on the benzene ring is very high, and a series of nucleophilic substitution reactions can occur. For example, halogen atoms can be introduced at the 5th position of the benzene ring, including chlorine, Bromine, iodine. |
| Synthesis method | For the synthesis of methyl 2-methoxy-4-aminobenzoate, the conventional synthesis method is from 2-methoxy-4-nitrobenzoate Starting from methyl ester, the target product is obtained by reducing the nitro group to the amino group through the reduction reaction. The commonly used reduction condition is palladium-carbon hydrogenation. Generally speaking, the hydrogen pressure used under this reaction condition often exceeds an atmospheric pressure. |
Last Update：2024-04-09 02:00:07
Supplier List
Spot supply
Product Name: Methyl 4-amino-2-methoxybenzoate Request for quotationCAS: 27492-84-8
Tel: +86-18162425036
Email: 3866263148@qq.com
Mobile: 18162425036
QQ: 3866263148
Wechat: 18162425036
Spot supply
Product Name: Amisulpride Impurity 20 Visit Supplier Webpage Request for quotationCAS: 27492-84-8
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: Methyl 4-amino-2-methoxybenzoate Request for quotation
CAS: 27492-84-8
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 27492-84-8
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Spot supply
Product Name: Methyl 4-amino-2-methoxybenzoate Visit Supplier Webpage Request for quotationCAS: 27492-84-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: Methyl 4-amino-2-methoxybenzoate Request for quotationCAS: 27492-84-8
Tel: +86-18162425036
Email: 3866263148@qq.com
Mobile: 18162425036
QQ: 3866263148
Wechat: 18162425036
Spot supply
Product Name: Amisulpride Impurity 20 Visit Supplier Webpage Request for quotationCAS: 27492-84-8
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: Methyl 4-amino-2-methoxybenzoate Request for quotation
CAS: 27492-84-8
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 27492-84-8
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Spot supply
Product Name: Methyl 4-amino-2-methoxybenzoate Visit Supplier Webpage Request for quotationCAS: 27492-84-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History